Zenicure Labs

• Levocetirizine Dihydrochloride 10 mg

  • A third-generation antihistamine.

  • Derived from cetirizine, but more potent and with fewer side effects.

• Relief from allergic rhinitis (sneezing, runny nose, nasal congestion).

• Treatment of chronic idiopathic urticaria (hives, itching).

• Helps with seasonal allergies like pollen, dust, or pet dander.

• Reduces symptoms such as watery eyes, itching, and throat irritation.

• Levocetirizine Dihydrochloride 5 mg

  • A third-generation antihistamine.

  • It is the active enantiomer of cetirizine, designed to be more effective with fewer side effects.

• Relief from seasonal allergic rhinitis (hay fever: sneezing, runny nose, itchy/watery eyes).

• Treatment of perennial allergic rhinitis (year-round allergies like dust mites, pet dander).

• Management of chronic idiopathic urticaria (persistent hives and itching).

• Helps reduce histamine-related symptoms such as swelling, redness, and irritation.

Flutisky (Fluticasone Furoate 27.5 mcg) is a nasal spray used to relieve symptoms of allergic rhinitis such as sneezing, runny nose, nasal congestion, and sinus discomfort. It is a corticosteroid that works by reducing inflammation in the nasal passages.

• Composition: Each spray contains Fluticasone Furoate 27.5 mcg.

• Type: Corticosteroid nasal spray.

• Uses:

  • Relieves seasonal and perennial allergic rhinitis.

  • Reduces sneezing, itching, runny nose, and nasal congestion.

  • Helps with sinus pressure and sometimes nasal polyps (with other treatment).

• How it works: Blocks chemical messengers (like histamines) that cause inflammation and allergy symptoms.

Flutisky-Az is a combination nasal spray that contains:

• Fluticasone Propionate (50 mcg) – a corticosteroid that reduces inflammation in the nasal passages.

• Azelastine Hydrochloride (140 mcg) – an antihistamine that blocks histamine receptors to relieve sneezing, itching, and runny nose.

🌿 Therapeutic Use

• Indicated for moderate to severe allergic rhinitis (both seasonal and perennial).

• Provides dual action:

  • Anti-inflammatory (from fluticasone)

  • Antihistamine (from azelastine)

• More effective than monotherapy for patients with persistent allergy symptoms.

💊 Dosage & Administration

• Typical regimen (adults & adolescents ≥12 years):

  • 1 spray per nostril twice daily (but always follow physician’s prescription).

• Each spray delivers a metered dose of 50 mcg fluticasone + 140 mcg azelastine.

• Bottle sizes usually provide 120 metered doses 

Zenifexo-120 is a brand of Fexofenadine Hydrochloride 120 mg, a second-generation non-sedating antihistamine.

• Class: Antihistamine (H1 receptor blocker).

• Mechanism: Prevents histamine from binding to its receptors, thereby reducing allergy symptoms like sneezing, runny nose, itchy/watery eyes, and skin hives.

• Non-sedating: Unlike older antihistamines (e.g., Hydroxyzine, Diphenhydramine), fexofenadine does not usually cause drowsiness.

• Seasonal allergic rhinitis (hay fever)

• Chronic idiopathic urticaria (hives)

• Relief from itching and swelling due to allergic reactions.

• Adults & children ≥12 years:

  • 120 mg once daily for allergic rhinitis.

  • 180 mg once daily sometimes prescribed for chronic urticaria.

• Children 6–11 years: Usually 30 mg twice daily (lower strength formulations).

Zenifexo-180 is a brand formulation of Fexofenadine Hydrochloride 180 mg, a second-generation, non-sedating antihistamine.

• Class: Antihistamine (H1 receptor blocker).

• Mechanism: Prevents histamine from binding to H1 receptors, reducing allergy symptoms such as sneezing, runny nose, itchy/watery eyes, and hives.

• Non-sedating: Unlike older antihistamines (e.g., Hydroxyzine, Diphenhydramine), fexofenadine rarely causes drowsiness.

• Chronic idiopathic urticaria (hives): 180 mg is the preferred dose for long-term management.

• Seasonal allergic rhinitis (hay fever): Sometimes prescribed when symptoms are more severe.

• Provides relief from itching, swelling, and redness due to allergic reactions.

• Adults & adolescents ≥12 years:

  • 180 mg once daily (usually for hives).

  • 120 mg once daily is often used for allergic rhinitis.

• Children 6–11 years: Lower strength (30 mg twice daily) is recommended.

Zeniflu-Plus is a multi-ingredient tablet designed to provide relief from cold, flu, and allergy-related symptoms, while also addressing pain and fever.

🌿 Composition & Role of Each Ingredient

• Aceclofenac (100 mg):

  • Non-steroidal anti-inflammatory drug (NSAID).

  • Reduces pain, inflammation, and swelling.

• Paracetamol (325 mg):

  • Analgesic and antipyretic.

  • Relieves pain and lowers fever.

• Cetirizine (10 mg):

  • Second-generation antihistamine.

  • Controls allergy symptoms like sneezing, runny nose, and itching.

• Phenylephrine (5 mg):

  • Nasal decongestant.

  • Shrinks swollen blood vessels in nasal passages, easing congestion.

• Caffeine (25 mg):

  • Mild stimulant.

  • Enhances alertness and may counteract drowsiness caused by cetirizine.

  • Sometimes used to boost pain-relief effect of paracetamol.

💊 Clinical Uses

• Relief from common cold and flu symptoms (fever, headache, body ache, nasal congestion).

• Allergic rhinitis (sneezing, runny nose, watery eyes).

• Sinus congestion and associated pain.

• General 

Zeniflu Cold is a combination medicine formulated to relieve common cold and flu symptoms. It contains multiple active ingredients that work together to reduce fever, pain, nasal congestion, and allergy-related discomfort.

• Caffeine (30 mg):

  • Mild stimulant.

  • Helps reduce fatigue and enhances alertness.

  • Sometimes added to boost the pain-relieving effect of paracetamol.

• Diphenhydramine (25 mg):

  • First-generation antihistamine.

  • Relieves sneezing, runny nose, watery eyes, and itching.

  • Has sedative properties, which can help with sleep but may cause drowsiness.

• Paracetamol (500 mg):

  • Analgesic and antipyretic.

  • Reduces fever, headache, sore throat, and body aches.

• Phenylephrine (5 mg):

  • Nasal decongestant.

  • Shrinks swollen blood vessels in nasal passages, easing congestion and sinus pressure.

• Relief from common cold and flu symptoms (fever, headache, body ache, nasal congestion).

• Allergic rhinitis (sneezing, runny nose, watery eyes).

• Sinus congestion and associated pain.

• Helps improve alertness while counteracting drowsiness from diphenhydramine.

   

Zenikast-Am is a bilayered tablet that combines three active ingredients for comprehensive relief in respiratory and allergic conditions:

• Ambroxol (75 mg): A mucolytic agent that thins and loosens mucus in the airways, making it easier to cough out.

• Levocetirizine (5 mg): A second-generation antihistamine that reduces allergy symptoms like sneezing, runny nose, and itching.

• Montelukast (10 mg): A leukotriene receptor antagonist that prevents airway inflammation and helps control asthma and allergic rhinitis.

• Allergic rhinitis (seasonal and perennial)

• Asthma prophylaxis (helps prevent attacks triggered by allergies)

• Chronic obstructive pulmonary disease (COPD) adjunct therapy

• Respiratory tract infections with excessive mucus and allergic symptoms

• Relief from nasal congestion, cough with phlegm, sneezing, and breathing difficulty

• Adults & adolescents ≥12 years: Usually 1 tablet once daily (doctor decides exact regimen).

• Bilayered design: Ensures controlled release of ingredients for sustained effect.

• Best taken in the evening to maximize control of nighttime allergy/asthma symptoms.

Zenikast-Bl is a combination tablet that contains:

• Bilastine (20 mg): A modern, second-generation antihistamine. It blocks histamine H1 receptors to relieve allergy symptoms such as sneezing, runny nose, itchy/watery eyes, and hives. Bilastine is non-sedating, so it generally does not cause drowsiness.

• Montelukast (10 mg): A leukotriene receptor antagonist. It prevents airway inflammation and reduces symptoms like nasal congestion, wheezing, and breathing difficulty, especially in asthma triggered by allergies.

• Seasonal allergic rhinitis (hay fever)

• Perennial allergic rhinitis (year-round allergies)

• Asthma prophylaxis (helps prevent attacks when allergies are a trigger)

• Relief from nasal congestion, sneezing, itching, watery eyes, and breathing difficulty

• Adults & adolescents ≥12 years: Usually 1 tablet once daily (doctor decides exact regimen).

• Best taken in the evening to maximize control of nighttime allergy/asthma symptoms.

• Should be swallowed whole with water, not chewed.

• Terbutaline Sulphate: 1.25 mg

  • Bronchodilator → relaxes airway muscles, relieves wheezing and breathlessness.

• Guaiphenesin: 50 mg

  • Expectorant → helps loosen and expel mucus, making coughs more productive.

• Bromhexine Hydrochloride: 4 mg

  • Mucolytic → breaks down thick mucus, improving clearance from the lungs.

• Menthol: 2.5 mg

  • Provides soothing, cooling effect on throat and reduces irritation.

👉 So, one 5 ml dose of Zenikuff‑BR syrup = 57.75 mg total active ingredients (1.25 + 50 + 4 + 2.5).

Zenikuff‑BR is prescribed for:

• Productive cough (cough with phlegm)

• Asthma and bronchospasm relief

• Chronic bronchitis

• COPD (Chronic Obstructive Pulmonary Disease)

• Respiratory tract infections with mucus buildup

• Nimesulide: 100 mg

  • NSAID (non‑steroidal anti‑inflammatory drug) → reduces pain, fever, and inflammation.

• Paracetamol (Acetaminophen): 325 mg

  • Analgesic & antipyretic → relieves pain and lowers fever.

• Phenylephrine Hydrochloride: 5 mg

  • Nasal decongestant → shrinks swollen nasal passages, relieves stuffy nose and sinus pressure.

• Caffeine: 25 mg

  • Mild stimulant → reduces fatigue, enhances alertness, and sometimes boosts pain relief.

👉 Bilayer tablet means the drug is formulated in two layers, often to separate immediate‑release and sustained‑release components for better therapeutic effect.

Zenisulide‑F is prescribed for cold, flu, and sinus conditions with fever and pain, especially when multiple symptoms occur together:

• Fever and body pain (due to Nimesulide + Paracetamol)

• Nasal congestion and sinus pressure (due to Phenylephrine)

• Fatigue and drowsiness relief (due to Caffeine)

• Common cold, flu, sinusitis, and allergic rhinitis with associated pain and fever

• Dextromethorphan Hydrobromide: 10 mg

  • Cough suppressant → acts on the brain’s cough center to reduce dry, irritating cough.

• Chlorpheniramine Maleate: 2 mg

  • Antihistamine → relieves allergy symptoms such as sneezing, runny nose, watery eyes, and throat irritation.

• Phenylephrine Hydrochloride: 5 mg

  • Nasal decongestant → shrinks swollen nasal passages, relieves stuffy nose and congestion.

👉 So, one Zenikuff‑DX softgel capsule = 17 mg total active ingredients (10 + 2 + 5).

Zenikuff‑DX is prescribed for:

• Dry cough (non‑productive cough)

• Cold and flu symptoms (nasal congestion, sneezing, runny nose, throat irritation)

• Allergic cough with nasal blockage

• Upper respiratory tract infections with persistent dry cough and congestion

Zenikast-LC (Levocetirizine 5 mg + Montelukast 10 mg) is a prescription combination tablet used to treat allergic rhinitis and asthma-related symptoms such as sneezing, runny nose, watery eyes, congestion, and breathing difficulties. It combines an antihistamine (Levocetirizine) with a leukotriene receptor antagonist (Montelukast) for dual relief.

• Levocetirizine Dihydrochloride (5 mg):

  • A second-generation antihistamine.

  • Reduces symptoms like sneezing, itching, watery eyes, and runny nose.

• Montelukast (10 mg):

  • A leukotriene receptor antagonist.

  • Prevents airway inflammation, reduces bronchospasm, and improves breathing.

• Allergic rhinitis (seasonal or perennial) – sneezing, nasal congestion, watery eyes.

• Asthma prophylaxis – helps prevent asthma attacks triggered by allergens.

• Chronic urticaria (hives) – reduces itching and swelling.

• Other allergic conditions where both histamine and leukotrienes play a role.

• Typically one tablet daily, taken with or without food.

• Dosage may vary depending on age, weight, and medical history.

• Important:Always follow a doctor’s prescription; do not self-medicate.

• Ambroxol Hydrochloride: 15 mg

  • Mucolytic agent → thins and loosens mucus in the airways.

• Terbutaline Sulphate: 1.25 mg

  • Bronchodilator → relaxes airway muscles, relieves wheezing and breathlessness.

• Guaiphenesin: 50 mg

  • Expectorant → helps expel mucus by making coughs more productive.

• Menthol: 2.5 mg

  • Provides soothing effect on throat, reduces irritation, and gives cooling sensation.

👉 So, one 5 ml dose of Zenikuff‑AM syrup = 68.75 mg total active ingredients (15 + 1.25 + 50 + 2.5).

• Productive cough (cough with phlegm)

• Asthma and bronchospasm relief

• Chronic bronchitis

• COPD (Chronic Obstructive Pulmonary Disease)

• Respiratory tract infections with mucus buildup

�� Composition (Per Tablet)

• Acebrophylline: 200 mg

  • A bronchodilator and mucolytic agent.

  • Helps relax airway muscles and reduce mucus viscosity, making breathing easier.

• Desloratadine: 5 mg

  • A non‑sedating antihistamine.

  • Relieves allergy symptoms like sneezing, runny nose, and itching.

• Montelukast: 10 mg

  • A leukotriene receptor antagonist.

  • Prevents airway inflammation and reduces bronchospasm.

Zenikast‑3D is prescribed for:

• Asthma management (especially allergic asthma).

• Chronic obstructive pulmonary disease (COPD) with mucus hypersecretion.

• Allergic rhinitis (seasonal or perennial).

• Chronic bronchitis : and other airway inflammatory conditions.

• Fexofenadine Hydrochloride: 120 mg

  • A non‑sedating antihistamine.

  • Relieves allergy symptoms like sneezing, runny nose, itchy/watery eyes, and skin rashes.

• Montelukast: 10 mg

  • A leukotriene receptor antagonist.

  • Prevents airway inflammation, reduces bronchospasm, and helps in asthma/allergic rhinitis.

👉 So, one tablet of Zenikast‑Fx = 120 mg Fexofenadine + 10 mg Montelukast. Total strength per tablet = 130 mg of active ingredients.

• Seasonal allergic rhinitis (hay fever).

• Chronic urticaria (hives).

• Asthma prophylaxis (especially allergy‑triggered asthma).

• Combined allergic conditions where both histamine and leukotrienes are involved.

• Levosalbutamol: 1 mg

  • A bronchodilator (relaxes airway muscles).

  • Helps relieve wheezing, shortness of breath, and bronchospasm.

• Ambroxol: 30 mg

  • A mucolytic agent (thins and loosens mucus).

  • Makes it easier to cough out phlegm and clear the airways.

• (Usually combined with Guaifenesin 50 mg or similar expectorant)

  • Helps in expelling mucus from the respiratory tract.

  • Some formulations may also include menthol or other soothing agents.

Zenikuff‑LS is prescribed for:

• Asthma and bronchospasm relief

• Chronic bronchitis

• COPD (Chronic Obstructive Pulmonary Disease)

• Respiratory tract infections with thick mucus

• Cough with phlegm (productive cough)

•  Nimesulide: 100 mg

  • Non‑steroidal anti‑inflammatory drug (NSAID) → reduces pain, fever, and inflammation.

• Phenylephrine Hydrochloride: 10 mg

  • Nasal decongestant → shrinks swollen nasal passages, relieves stuffy nose.

• Cetirizine Hydrochloride: 5 mg

  • Antihistamine → relieves allergy symptoms like sneezing, runny nose, watery eyes, itching.

• Caffeine: 30 mg

  • Mild stimulant → reduces fatigue, enhances alertness, and sometimes added to improve pain relief.

👉 Bilayer tablet means the drug is formulated in two layers, often to separate immediate‑release and sustained‑release components for better therapeutic effect.

Zenisulide‑C is prescribed for cold, flu, and allergy‑related symptoms, especially when accompanied by pain or fever:

• Fever and body pain (due to Nimesulide)

• Nasal congestion and sinus pressure (due to Phenylephrine)

• Allergic symptoms like sneezing, runny nose, watery eyes (due to Cetirizine)

• Fatigue and drowsiness relief (due to Caffeine)

• Common cold, flu, sinusitis, and allergic rhinitis

Zenikuff‑LR (Levocloperastine 20mg + Chlorpheniramine 4mg) is primarily used for the treatment of dry cough associated with allergies and upper respiratory tract infections. It combines a cough suppressant with an antihistamine to provide dual relief.

• Dry cough (non‑productive)

  • Suppresses persistent cough by acting on the cough center in the brain.

• Allergic cough & rhinitis

  • Relieves sneezing, runny nose, and throat irritation caused by allergies.

• Upper respiratory tract infections (URTI)

  • Symptomatic relief in pharyngitis, laryngitis, and post‑nasal drip.

• Cough associated with allergy or seasonal changes

  • Useful in patients with allergic rhinitis or hay fever.

• Levocloperastine (20mg):

  • Centrally acting cough suppressant → reduces activity of the cough center in the brain.

  • Provides relief without the sedative or addictive risks of opioids.

• Chlorpheniramine (4mg):

  • Antihistamine → blocks histamine receptors, reducing allergic symptoms like sneezing, watery eyes, and nasal congestion.

👉 Together: Suppresses dry cough + controls allergy symptoms, improving breathing comfort.

This formulation combines three active ingredients commonly found in cough mixtures:

• Class: First-generation antihistamine

• Action:

  • Reduces allergic symptoms (runny nose, sneezing)

  • Has sedative properties, which can help with nighttime cough relief

• Note: Can cause drowsiness, dry mouth, blurred vision, and sometimes constipation

• Class: Expectorant

• Action:

  • Helps loosen and thin mucus in the airways

  • Makes coughing more productive by clearing phlegm

• Class: Mucolytic / Alkalinizing agent

• Action:

  • Reduces the acidity of mucus

  • Helps break down thick phlegm, easing its removal

• Often used as a solvent and preservative in cough syrups

• Can enhance sedative effects of diphenhydramine

• Caution: Not suitable for children, pregnant women, or people with liver disease, alcohol dependence, or those taking other sedating medications

Momedot is a nasal spray formulation that contains Mometasone Furoate 50 mcg per spray.

• Class: Corticosteroid (glucocorticoid).

• Mechanism: Reduces inflammation in nasal passages by blocking the release of inflammatory mediators.

• Formulation: Each metered spray delivers 50 mcg of Mometasone Furoate.

• Seasonal allergic rhinitis (hay fever)

• Perennial allergic rhinitis (year-round allergies)

• Nasal polyps (to reduce size and symptoms)

• Sinusitis adjunct therapy (sometimes used with antibiotics)

• Adults & children ≥12 years: Usually 2 sprays per nostril once daily (total 200 mcg/day).

• Children 6–11 years: Often 1 spray per nostril once daily (total 100 mcg/day).

• Onset: Relief may begin within 12 hours, but full effect can take a few days.

• Pack size:Typically available in bottles with 120 metered doses.

Zenifexo-M is a combination tablet containing:

• Fexofenadine Hydrochloride 120 mg – a second-generation, non-sedating antihistamine.

• Montelukast 10 mg – a leukotriene receptor antagonist.

• Fexofenadine (120 mg): Blocks histamine (H1 receptors), reducing sneezing, runny nose, itchy/watery eyes, and hives.

• Montelukast (10 mg): Blocks leukotrienes, chemicals that cause airway inflammation, swelling, and mucus production.

Together, they provide dual action against allergic rhinitis and asthma-related symptoms.

• Seasonal allergic rhinitis (hay fever)

• Perennial allergic rhinitis (year-round allergies)

• Asthma prophylaxis (helps prevent asthma attacks when allergies are a trigger)

• Relief from nasal congestion, sneezing, itching, watery eyes, and breathing difficulty

• Adults & adolescents ≥12 years: Typically 1 tablet once daily (as prescribed).

• Best taken in the evening for asthma/allergy control.

• Should be swallowed whole with water, not chewed.

   

Hybud-25 is a brand formulation that contains Hydroxyzine Hydrochloride 25 mg.

• Class: First-generation antihistamine.

• Mechanism: Blocks histamine (H1) receptors, reducing allergy symptoms. Also has sedative and anxiolytic properties due to effects on the central nervous system.

• Allergic conditions: Relief from itching, hives, and allergic rhinitis.

• Anxiety: Sometimes prescribed short-term for anxiety symptoms.

• Sleep aid: Due to sedative effects, occasionally used for insomnia.

• Adjunct in anesthesia: Helps with sedation before or after surgery.

• Nausea/vomiting:Can be used in some cases.

• Levodropropizine: 30 mg

  • Non‑opioid cough suppressant → reduces dry, irritating cough by acting on peripheral sensory nerves (not the brain’s cough center like Dextromethorphan).

• Chlorpheniramine Maleate: 2 mg

  • Antihistamine → relieves allergy symptoms such as sneezing, runny nose, watery eyes, and throat irritation.

�� So, one 5 ml dose of Zenikuff‑LC syrup = 32 mg total active ingredients (30 + 2).

Zenikuff‑LC is prescribed for:

• Dry cough (non‑productive cough)

• Allergic cough with sneezing and runny nose

• Cold and flu symptoms with throat irritation

• Upper respiratory tract infectionswith persistent dry cough

• Doxycycline (100 mg):

  • A tetracycline-class broad-spectrum antibiotic.

  • Works by inhibiting bacterial protein synthesis, stopping growth and spread.

  • Commonly used for respiratory infections, skin infections, sexually transmitted infections, and certain fevers (like typhoid, malaria prophylaxis).

• Lactobacillus (60 million spores):

  • A probiotic that restores healthy gut bacteria.

  • Helps reduce antibiotic-associated diarrhea, bloating, and stomach upset.

  • Supports digestion and immunity during antibiotic therapy.

This combination is prescribed for:

• Respiratory tract infections (bronchitis, pneumonia)

• Urinary tract infections (UTIs)

• Skin and soft tissue infections (acne, boils, cellulitis)

• Sexually transmitted infections (chlamydia, syphilis)

• Typhoid fever and other gastrointestinal infections

• Preventing antibiotic-associated diarrhea (thanks to Lactobacillus)