Zenicure Labs

Methylcure‑OD (Methylcobalamin 1500 mcg + Alpha Lipoic Acid 100mg + Pyridoxine 10mg + Folic Acid 1.5mg Capsules) is a neuroprotective and antioxidant combination designed for comprehensive support in neuropathies and nerve regeneration.

• Diabetic Neuropathy

  • Relieves tingling, numbness, and burning sensations in extremities.

• Peripheral Neuropathy

  • Supports nerve repair and regeneration.

• Neurodegenerative Disorders

  • Provides antioxidant protection and improves neuronal function.

• Adjunct in Vitamin Deficiency States

  • Corrects B‑complex and folate deficiencies contributing to nerve dysfunction.

Neurive‑CD3 (Calcium Citrate + Alpha Lipoic Acid + Benfotiamine + Chromium Polynicotinate + Folic Acid + Inositol + Methylcobalamin + Pyridoxine + Vitamin D3) is a comprehensive neuro‑metabolic support capsule designed for diabetic neuropathy, nerve regeneration, and metabolic balance.

• Diabetic Neuropathy

  • Relieves tingling, numbness, and burning sensations in extremities.

• Peripheral Neuropathy & Neurodegeneration

  • Supports nerve repair, regeneration, and antioxidant protection.

• Metabolic Syndrome / Diabetes Support

  • Chromium polynicotinate helps regulate glucose metabolism.

• Bone & Nerve Health

  • Calcium citrate + Vitamin D3 strengthen bones and improve neuromuscular function.

• Cognitive & Mood Support

  • Inositol and B‑complex vitamins aid neurotransmitter balance.

• Calcium Citrate (500mg): Improves bone strength and neuromuscular signaling.

• Alpha Lipoic Acid (200mg): Potent antioxidant → reduces oxidative stress in nerves.

• Benfotiamine (150mg): Fat‑soluble B1 → prevents advanced glycation end products (AGEs) in diabetes.

• Chromium Polynicotinate (200mcg): Enhances insulin sensitivity and glucose metabolism.

• Folic Acid (1.5mg): Supports DNA synthesis and synergizes with B12 for neuroprotection.

• Inositol (100mg): Improves neurotransmitter signaling, mood, and nerve conduction.

• Methylcobalamin (1500mcg): Active B12 → repairs myelin sheath, enhances nerve conduction.

• Pyridoxine (3mg): Essential for neurotransmitter synthesis.

• Vitamin D3 (1000 IU): Strengthens bones, supports immune and neuromuscular health.

• Neurive‑Forte (Thiamine Mononitrate 10mg + Riboflavin 10mg + Pyridoxine Hydrochloride 3mg + Cyanocobalamin 15mcg + Nicotinamide 45mg + Calcium Pantothenate 50mg Capsules) is a neuro‑vitamin complex designed to support nerve health, energy metabolism, and overall vitality.

  �� Key Medical Uses

  • Peripheral Neuropathy

    • Relieves tingling, numbness, and burning sensations in extremities.

  • Diabetic Neuropathy

    • Provides B‑complex support for nerve repair and regeneration.

  • Vitamin Deficiency States

    • Corrects B‑vitamin deficiencies that impair nerve and metabolic function.

  • Fatigue & Weakness

    • Improves energy metabolism and reduces tiredness.

  • Adjunct in Neurodegenerative Disorders

    • Supports neuronal function and neurotransmitter synthesis.

  �� Component Rationale

  • Thiamine (B1, 10mg): Essential for carbohydrate metabolism and nerve conduction.

  • Riboflavin (B2, 10mg): Supports energy production and antioxidant defense.

  • Pyridoxine (B6, 3mg): Key for neurotransmitter synthesis and nerve function.

  • Cyanocobalamin (B12, 15mcg): Supports myelin sheath repair and red blood cell formation.

  • Nicotinamide (B3, 45mg): Improves cellular energy and skin health.

  • Calcium Pantothenate (B5, 50mg): Vital for coenzyme A synthesis → energy metabolism and stress response.

  • “Neurive‑Forte – Complete B‑Complex Neuro Support for Energy & Nerve Health.”

Neurive‑GM (Gabapentin 300mg + Methylcobalamin 500mcg Tablets) is a neuroprotective and neuropathic pain management combination widely prescribed in neurology and diabetology.

• Diabetic Neuropathy

  • Relieves burning, tingling, and numbness in extremities.

• Peripheral Neuropathy

  • Supports nerve repair and reduces neuropathic pain.

• Post‑herpetic Neuralgia

  • Effective in nerve pain following shingles.

• Neuropathic Pain Syndromes

  • Useful in sciatica, radiculopathy, and chronic nerve pain conditions.

• Gabapentin (300mg):

  • Modulates calcium channels in neurons → reduces abnormal nerve excitability.

  • Provides analgesic effect in neuropathic pain.

• Methylcobalamin (500mcg):

  • Active form of Vitamin B12 → promotes myelin sheath repair and enhances nerve conduction.

• Together:

  • Dual benefit → pain relief + nerve regeneration.

Neurive‑GN 100 (Gabapentin 100mg + Nortriptyline 10mg Tablets) is a dual‑action therapy combining an anticonvulsant with a tricyclic antidepressant, widely used for neuropathic pain management and nerve health.

• Diabetic Neuropathy

  • Relieves burning, tingling, and numbness in extremities.

• Peripheral Neuropathy

  • Supports nerve repair and reduces chronic nerve pain.

• Post‑herpetic Neuralgia

  • Effective in nerve pain following shingles.

• Neuropathic Pain Syndromes

  • Useful in sciatica, radiculopathy, and fibromyalgia.

Neurive‑GN (Gabapentin 400mg + Nortriptyline 10mg Tablets) is a dual‑action therapy combining an anticonvulsant with a tricyclic antidepressant, specifically designed for neuropathic pain management and nerve health.

• Diabetic Neuropathy

  • Relieves burning, tingling, and numbness in extremities.

• Peripheral Neuropathy

  • Supports nerve repair and reduces chronic nerve pain.

• Post‑herpetic Neuralgia

  • Effective in nerve pain following shingles.

• Neuropathic Pain Syndromes

  • Useful in sciatica, radiculopathy, fibromyalgia, and chronic pain conditions.

• Gabapentin (400mg):

  • Modulates calcium channels in neurons → reduces abnormal excitability.

  • Provides analgesic effect in neuropathic pain.

• Nortriptyline (10mg):

  • Tricyclic antidepressant → inhibits serotonin & norepinephrine reuptake.

  • Enhances pain modulation and improves mood.

• Together:

  • Synergistic action → pain relief + mood stabilization + nerve protection.

Neurive‑GN 300 (Gabapentin 300mg + Nortriptyline 10mg Tablets) is a dual‑action therapy combining an anticonvulsant with a tricyclic antidepressant, widely prescribed for neuropathic pain management and nerve health.

• Diabetic Neuropathy

  • Relieves burning, tingling, and numbness in extremities.

• Peripheral Neuropathy

  • Supports nerve repair and reduces chronic nerve pain.

• Post‑herpetic Neuralgia

  • Effective in nerve pain following shingles.

• Neuropathic Pain Syndromes

  • Useful in sciatica, radiculopathy, fibromyalgia, and chronic pain conditions.

• Gabapentin (300mg):

  • Modulates calcium channels in neurons → reduces abnormal excitability.

  • Provides analgesic effect in neuropathic pain.

• Nortriptyline (10mg):

  • Tricyclic antidepressant → inhibits serotonin & norepinephrine reuptake.

  • Enhances pain modulation and improves mood.

• Together:

  • Synergistic action → pain relief + mood stabilization + nerve protection.

Neurive‑LC (Levo‑Carnitine 500mg + Methylcobalamin 1500mcg + Folic Acid 1.5mg Tablets) is a neuro‑metabolic support formulation designed for neuropathic pain, nerve regeneration, and energy metabolism.

• Diabetic Neuropathy

  • Relieves tingling, numbness, and burning sensations in extremities.

• Peripheral Neuropathy

  • Supports nerve repair and regeneration.

• Neurodegenerative Disorders

  • Provides antioxidant and neuroprotective support.

• Fatigue & Muscle Weakness

  • Levo‑Carnitine improves mitochondrial energy metabolism.

• Levo‑Carnitine (500mg):

  • Facilitates fatty acid transport into mitochondria → boosts cellular energy.

  • Reduces fatigue and supports muscle + nerve health.

• Methylcobalamin (1500mcg):

  • Active form of Vitamin B12 → repairs myelin sheath, enhances nerve conduction.

• Folic Acid (1.5mg):

  • Supports DNA synthesis and synergizes with B12 for neuroprotection.

• Together:

  • Triple action → energy metabolism + nerve repair + neuroprotection.

Neurive‑Plus (Alpha Lipoic Acid 100mg + Folic Acid 1.5mg + Methylcobalamin 1500mcg + Vitamin D3 1000 IU + Benfotiamine 7.5mg + Biotin 5mcg + Inositol 1.5mg Capsules) is a multi‑component neuroprotective and metabolic support formulation designed for diabetic neuropathy, nerve regeneration, and overall cellular health.

• Diabetic Neuropathy

  • Relieves tingling, numbness, and burning sensations in extremities.

• Peripheral Neuropathy & Neurodegeneration

  • Supports nerve repair, regeneration, and antioxidant protection.

• Metabolic Syndrome / Diabetes Support

  • Benfotiamine prevents advanced glycation end products (AGEs).

• Bone & Nerve Health

  • Vitamin D3 + Calcium metabolism synergy for neuromuscular strength.

• Cognitive & Mood Support

  • Inositol and B‑complex vitamins aid neurotransmitter balance.

• Alpha Lipoic Acid (100mg): Potent antioxidant → reduces oxidative stress, improves microcirculation in nerves.

• Folic Acid (1.5mg): Supports DNA synthesis and synergizes with B12 for neuroprotection.

• Methylcobalamin (1500mcg): Active B12 → repairs myelin sheath, enhances nerve conduction.

• Vitamin D3 (1000 IU): Strengthens bones, supports immune and neuromuscular health.

• Benfotiamine (7.5mg): Fat‑soluble B1 → prevents diabetic complications via AGE inhibition.

• Biotin (5mcg): Supports cellular metabolism and skin/nail health.

• Inositol (1.5mg): Improves neurotransmitter signaling, mood, and nerve conduction.

Neurive‑GM 100 (Gabapentin 100mg + Methylcobalamin 500mcg Tablets) is a neuroprotective and neuropathic pain management combination formulated for early‑stage or milder neuropathic conditions, offering both pain relief and nerve repair support.

• Diabetic Neuropathy

  • Relieves tingling, burning, and numbness in extremities.

• Peripheral Neuropathy

  • Supports nerve regeneration and reduces discomfort.

• Post‑herpetic Neuralgia

  • Effective in nerve pain following shingles.

• Neuropathic Pain Syndromes

  • Useful in sciatica, radiculopathy, and chronic nerve pain conditions.

• Gabapentin (100mg):

  • Modulates calcium channels in neurons → reduces abnormal excitability.

  • Provides analgesic effect in neuropathic pain.

• Methylcobalamin (500mcg):

  • Active form of Vitamin B12 → promotes myelin sheath repair and enhances nerve conduction.

• Together:

  • Dual benefit → pain relief + nerve regeneration.

• 100mg Gabapentin strength:

  • Suitable for titration, elderly patients, or those requiring gentler initiation.

Zenicoxib‑PG (Pregabalin 75mg SR + Etoricoxib 60mg Bilayered Tablet) is a dual‑action formulation combining a neuropathic pain modulator with a selective COX‑2 inhibitor, designed for chronic pain management with both neurogenic and inflammatory components.

�� Key Medical Uses

• Neuropathic Pain Syndromes

  • Diabetic neuropathy, sciatica, radiculopathy, fibromyalgia.

• Chronic Musculoskeletal Pain

  • Osteoarthritis, rheumatoid arthritis, spondylosis.

• Mixed Pain Conditions

  • Cases where nerve pain overlaps with inflammatory pain.

�� Component Rationale

• Pregabalin 75mg (Sustained Release):

  • Modulates calcium channels → reduces abnormal neuronal excitability.

  • Provides long‑lasting analgesia for neuropathic pain.

• Etoricoxib 60mg:

  • Selective COX‑2 inhibitor → reduces prostaglandin synthesis.

  • Potent anti‑inflammatory and analgesic effect with lower GI risk compared to non‑selective NSAIDs.

• Bilayered Tablet:

  • Ensures controlled release of Pregabalin with effective anti‑inflammatory action of Etoricoxib.

• Together:

  • Dual synergy → Nerve pain relief + Inflammation control

Methylcure‑SR 75 (Pregabalin SR 75mg + Methylcobalamin 1500mcg Tablets) is a dual‑action sustained release formulation designed for neuropathic pain relief and nerve repair with improved compliance.

• Diabetic Neuropathy

  • Relieves tingling, burning, and numbness in extremities.

• Peripheral Neuropathy

  • Supports nerve regeneration and reduces chronic pain.

• Post‑herpetic Neuralgia & Fibromyalgia

  • Effective in chronic neuropathic pain syndromes.

• Neuropathic Pain Syndromes

  • Useful in sciatica, radiculopathy, and nerve compression disorders.

• Pregabalin SR (75mg):

  • Modulates calcium channels → reduces abnormal excitability.

  • Sustained release ensures longer duration of analgesia and better patient adherence.

• Methylcobalamin (1500mcg):

  • Active Vitamin B12 → repairs myelin sheath, enhances nerve conduction.

• Together:

  • Dual synergy → Pain relief + Nerve repair with sustained coverage.

•  

  Neurive‑PN (Pregabalin 75mg + Nortriptyline 10mg Tablets) is a dual‑action therapy combining an anticonvulsant with a tricyclic antidepressant, designed for neuropathic pain relief and mood stabilization.

  �� Key Medical Uses

  • Diabetic Neuropathy

    • Relieves burning, tingling, and numbness in extremities.

  • Peripheral Neuropathy

    • Supports nerve repair and reduces chronic pain.

  • Post‑herpetic Neuralgia & Fibromyalgia

    • Effective in chronic neuropathic pain syndromes.

  • Mood Disorders with Pain Component

    • Nortriptyline improves mood and enhances pain modulation.

  �� Component Rationale

  • Pregabalin (75mg):

    • Modulates calcium channels → reduces abnormal excitability.

    • Provides strong analgesic effect in neuropathic pain.

  • Nortriptyline (10mg):

    • Tricyclic antidepressant → inhibits serotonin & norepinephrine reuptake.

    • Enhances descending pain inhibition and stabilizes mood.

  • Together:

    • Dual synergy → Pain relief + Mood balance.

   

Neurive‑TRIO (Pregabalin 75mg Prolonged Release + Methylcobalamin 1500mcg + Nortriptyline 10mg Bilayered Tablet) is a triple‑action neuroprotective and neuropathic pain management formulation combining analgesic, neurotrophic, and antidepressant benefits in a single bilayered tablet.

• Diabetic Neuropathy

  • Relieves burning, tingling, and numbness in extremities.

• Peripheral Neuropathy

  • Supports nerve repair and reduces chronic pain.

• Post‑herpetic Neuralgia & Fibromyalgia

  • Effective in chronic neuropathic pain syndromes.

• Mood Disorders with Pain Component

  • Nortriptyline improves mood and enhances pain modulation.

• Pregabalin 75mg (Prolonged Release):

  • Modulates calcium channels → reduces abnormal excitability.

  • Provides sustained analgesic effect in neuropathic pain.

• Methylcobalamin 1500mcg:

  • Active Vitamin B12 → repairs myelin sheath, enhances nerve conduction.

• Nortriptyline 10mg:

  • Tricyclic antidepressant → inhibits serotonin & norepinephrine reuptake.

  • Enhances descending pain inhibition and stabilizes mood.

• Bilayered Tablet:

  • Ensures controlled release of Pregabalin with immediate action of Nortriptyline + B12.

• Together:

  • Triple synergy → Pain relief + Nerve repair + Mood balance.

•  

  Neurive‑PM (Pregabalin 75mg + Methylcobalamin 750mcg Tablets) is a dual‑action formulation combining an anticonvulsant with a neurotrophic vitamin, designed for neuropathic pain relief and nerve repair.

  �� Key Medical Uses

  • Diabetic Neuropathy

    • Relieves burning, tingling, and numbness in extremities.

  • Peripheral Neuropathy

    • Supports nerve regeneration and reduces chronic pain.

  • Post‑herpetic Neuralgia

    • Effective in nerve pain following shingles.

  • Neuropathic Pain Syndromes

    • Useful in sciatica, radiculopathy, and fibromyalgia.

  �� Component Rationale

  • Pregabalin (75mg):

    • Modulates calcium channels in neurons → reduces abnormal excitability.

    • Provides strong analgesic effect in neuropathic pain.

  • Methylcobalamin (750mcg):

    • Active Vitamin B12 → repairs myelin sheath, enhances nerve conduction.

  • Together:

    • Synergistic action → pain relief + nerve repair.

  • Balanced strength:

    • Pregabalin 75mg + mid‑dose B12 makes it suitable for step‑up therapy or maintenance.

   

Neurive‑PD20 (Pregabalin 75mg + Duloxetine DR 20mg Capsules) is a dual‑pathway therapy combining an anticonvulsant with an SNRI antidepressant, tailored for neuropathic pain relief and mood stabilization.

• Diabetic Neuropathy

  • Relieves burning, tingling, and numbness in extremities.

• Peripheral Neuropathy

  • Supports nerve repair and reduces chronic nerve pain.

• Fibromyalgia & Chronic Pain Syndromes

  • Effective in widespread musculoskeletal pain with associated fatigue.

• Mood Disorders with Pain Component

  • Duloxetine improves mood and reduces pain perception.

• Pregabalin (75mg):

  • Modulates calcium channels in neurons → reduces abnormal excitability.

  • Provides strong analgesic effect in neuropathic pain.

• Duloxetine DR (20mg):

  • Serotonin‑Norepinephrine Reuptake Inhibitor (SNRI).

  • Enhances descending pain inhibition pathways and improves mood.

DULORUSH‑20 is a branded formulation of Duloxetine Hydrochloride 20 mg, manufactured and marketed by Zenicure Labs under its PCD pharma model. Duloxetine is a serotonin‑norepinephrine reuptake inhibitor (SNRI) widely prescribed for depression, anxiety disorders, neuropathic pain, and fibromyalgia.

Zenicure Labs positions DULORUSH‑20 as part of its neuropsychiatric and pain management portfolio, combining therapeutic efficacy with strong distributor support. The gastro‑resistant coating ensures the drug bypasses stomach acid, improving absorption and reducing gastrointestinal side effects.

• Active Ingredient: Duloxetine Hydrochloride 20 mg

• Formulation: Gastro‑resistant tablet

• Excipients: Enteric coating polymers, stabilizers, disintegrants

• Packaging: Blister strips, typically 10 tablets per strip

The gastro‑resistant design is critical because Duloxetine is unstable in acidic environments. This ensures optimal bioavailability.

• Class: SNRI (Serotonin‑Norepinephrine Reuptake Inhibitor)

• Mechanism of Action:

  • Inhibits reuptake of serotonin (5‑HT) and norepinephrine (NE) at presynaptic neurons.

  • Enhances neurotransmission in central nervous system pathways regulating mood and pain.

• Therapeutic Effect: Antidepressant, anxiolytic, and analgesic.

DULORUSH‑20 is prescribed for:

• Major Depressive Disorder (MDD)

• Generalized Anxiety Disorder (GAD)

• Diabetic Peripheral Neuropathy (DPN)

• Fibromyalgia

• Chronic Musculoskeletal Pain

• Adults:

  • Initial dose: 20–30 mg once daily.

  • Maintenance: 40–60 mg/day (higher strengths available).

• Children/Adolescents: Not routinely recommended.

• Special Populations:

  • Renal impairment: Dose adjustment required.

  • Hepatic impairment: Contraindicated.

• Absorption: Delayed until tablet reaches intestine.

• Peak Plasma Concentration: 6 hours post‑dose.

• Protein Binding: >90%.

• Metabolism: Hepatic via CYP1A2 and CYP2D6.

• Excretion: Renal and fecal routes.

• Half‑Life: ~12 hours.

• Depression: Demonstrated efficacy in reducing Hamilton Depression Rating Scale (HAM‑D) scores.

• Anxiety: Effective in reducing GAD‑7 scores.

• Neuropathic Pain: Improves pain scores in diabetic neuropathy.

• Fibromyalgia: Reduces widespread pain and fatigue.

Neurive‑OD Forte (Pregabalin 75mg + Methylcobalamin 1500mcg + Alpha Lipoic Acid 100mg + Pyridoxine 3mg + Folic Acid 1.5mg Soft‑gel) is a comprehensive neuroprotective and neuropathic pain management formulation combining analgesic, antioxidant, and vitamin support.

• Diabetic Neuropathy

  • Relieves burning, tingling, and numbness in extremities.

• Peripheral Neuropathy

  • Supports nerve repair and regeneration.

• Post‑herpetic Neuralgia & Fibromyalgia

  • Effective in chronic neuropathic pain syndromes.

• Neurodegenerative Disorders

  • Provides antioxidant and neurotrophic support.

• Pregabalin (75mg):

  • Modulates calcium channels → reduces abnormal nerve excitability.

  • Provides strong analgesic effect in neuropathic pain.

• Methylcobalamin (1500mcg):

  • Active Vitamin B12 → repairs myelin sheath, enhances nerve conduction.

• Alpha Lipoic Acid (100mg):

  • Potent antioxidant → reduces oxidative stress, improves microcirculation in nerves.

• Pyridoxine (Vitamin B6, 3mg):

  • Supports neurotransmitter synthesis and nerve function.

• Folic Acid (1.5mg):

  • DNA synthesis and synergistic neuroprotection with B12.

• Together:

  • Triple synergy → Pain relief + Nerve repair + Antioxidant protection.